昭平县1～6岁儿童乙肝免疫效果调查

On the effects of hepatitis B immunization among children aged 1-6 years in Zhaoping county

目的了解昭平县1～6岁儿童乙肝疫苗免疫效果,为乙型肝炎的防控和乙肝疫苗接种提供科学理论依据。方法 2012年6月对昭平县150名儿童进行乙肝免疫效果调查,对所采集的血样采用美国雅培公司化学发光法定量检测HBsAg和HBsAb。结果共对150名儿童进行检测,HBsAg阳性率为0.67%(1/150),HBsAb阳性率为45.33%(68/150),性别之间HBsAb阳性率差异无统计学意义(P>0.05),各年龄组之间HBsAb阳性率差异有统计学意义(P<0.05)。结论昭平县1～6岁儿童HBsAg感染水平较低,HBsAb阳性率情况不容乐观,要加强乙肝防控知识的宣传,正确注射乙肝疫苗,加强抗体检测工作。

Objective To learn about the effects of hepatitis B immunization among children aged 1 - 6 years in Zhaoping county, so as to provide a scientific basis for the control and immunization of hepatitis B. Methods Collected blood sam- pies were quantitatively detected for HBsAg and HBsAh by eleetrochemilumineseenee method （ Abbott Laboratories）. Re- suits A total of 150 children were examined, among which HBsAg positive rate was 0.67% （1/150） and HBsAb positive rate 45.33% （68/150）. There was no significant difference between the sexes in HBsAb positive rate（ P 〉 0.05）, but significant difference was found between groups of different ages （ P 〈 0.05）. Conclusions HBsAg infection is in a low level among children aged 1 - 6 years in Zhaoping county and the situation of HBsAb positive rate is not optimistic. There- fore, health education on prevention and control of hepatitis B should be strengthened, vaccination given properly and antibody detection enhanced.