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RNA干扰抗人单股正链RNA病毒感染的研究进展 被引量：3

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摘要 RNA干扰（RNA interference，RNAi）技术是一种新兴的高效基因沉默工具，用于研究基因功能与基因表达调控领域，特异性地降低或关闭目的基因表达。近年来，针对病毒感染性疾病，尚无特别有效的防治方法。目前RNAi技术被广泛应用于抗病毒感染领域的研究，几种以RNAi为基础的抗病毒疗法目前正在进行不同时期的临床试验，有望成为抗病毒感染基因治疗的有效工具。
作者 邓军霞 张国成 雷迎峰
机构地区 西安第四军医大学西京医院儿科 第四军医大学基础医学院微生物学教研室
出处 《国际病毒学杂志》 2012年第6期283-288,共6页 International Journal of Virology
关键词 RNAI 单股正链RNA病毒 SIRNA 抗病毒
分类号 R51 [医药卫生—内科学]
  • 相关文献

参考文献24

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二级参考文献35

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共引文献1

同被引文献24

  • 1陈克平,唐旭东.RNAi技术研究进展[J].江苏大学学报（自然科学版）,2004,25(4):336-340. 被引量：4
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  • 3王皓,李玉勤,贺显君,王昆.RNA干扰技术的研究进展[J].医药论坛杂志,2005,26(7):77-79. 被引量：1
  • 4秦玉新,蒙凌华,丁健.RNA干扰技术的研究进展[J].中国药理学通报,2007,23(4):421-424. 被引量：21
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引证文献3

二级引证文献10

国际病毒学杂志
2012年 第6期

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