上海地区急性呼吸道感染患儿病毒病原学研究

Investigation on the viral etiology of acute respiratory tract infection in children in Shanghai

目的 探讨上海地区近 5年来急性呼吸道感染患儿病毒病原和支原体病原感染状况。方法 采用系列呼吸道病毒单克隆抗体桥联酶标法或聚合酶链反应技术 ,对上海地区 5年中的急性呼吸道感染患儿 5 496例标本进行病毒学或肺炎支原体 -DNA检测。结果 检出病毒阳性 2 2 5 7例 ,阳性率 41 0 7%以上 ,肺炎支原体 -DNA检出率 16 2 % (5 72 / 35 38)。结论 连续 5年中上海地区有 2次急性呼吸道病毒感染发病高峰 (1994年和 1998年 ) ,病毒性感染流行季节主要在每年 1～ 2月和 11～

Objective To study the infectious state of virus and mycoplasma pneumoniae leading to children's acute respiratory tract infection in recent 5 years in Shanghai area.Methods The method of monoclonal antibody bridge linked enzyme essay or PCR technique was used to test respiratory tract viruses and mycoplasma pneumoniae DNA respectively.A total of 5496 cases in 5 years were examined.Results 2257 cases were shown to be infected by virus and the positive rate was over 41\^07%.The positive rate of mycoplasma pneumoniae DNA was 16\^2%(572/3538).Conclusion It showed that there were 2 major epidemics(1994,1998)of respiratory tract virus infection in Shanghai area.The epidemics of virus infection occured in January,February,November and December every year in Shanghai.