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替罗非班在高龄急性冠脉综合征患者介入治疗中的应用剂量探讨 被引量:2

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摘要 替罗非班是血小板糖蛋白(GP)Ⅱb、Ⅲa受体拮抗剂.现已广泛应用于急性冠脉综合征(ACS)的治疗,并且能改善经皮冠状动脉介入治疗(PCI)后心肌组织供血.降低主要不良心血管事件发生。尽管替罗非班抗血小板疗效好、安全性高,但在高龄患者中,常规剂量替罗非班仍显著增加了主要出血事件发生,因此,在高龄患者中,其应用剂量尚有待进一步探讨。本研究旨在探讨75岁以上ACS患者接受PCI治疗时应用替罗非班的剂量和安全性。
出处 《中国现代医药杂志》 2012年第12期74-75,共2页 Modern Medicine Journal of China
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