静息心率与不同临床分型冠心病关系的探讨

Relationship between Resting Heart Rate and Coronary Syndrome

目的研究静息心率与稳定心绞痛及急性冠脉综合征的关系。方法2009年7月～2010年10月在本院住院的冠心病患者445例，分为稳定心绞痛组（S组，n=268）和急性冠脉综合征组（U组，n=177），分析静息心率与冠心病不良心血管事件发生的相关性。结果U组的静息心率明显高于S组（P〈0．01）。Logistic回归分析显示，校正年龄、舒张压、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、血尿酸、空腹血糖及餐后2h血糖等因素后，静息心率（OR=t．052，95％CI：1．009～1．097，P=-0．017）、收缩压（0R=1．027，95％CI：1．003-1．053，P=0．031）和甘油三酯（OR=2．743，95％CI：1．207～6．233，P=0．016）仍是冠心病的独立危险因素。结论静息心率是急性冠脉综合征的独立危险因素。

Objective To investigate the relationship between resting heart rate （RHR） and coronary heart disease （CHD） and to explore the value of RHR in predicting the occurrence of acute coronary syndrome. Methods 445 patients with CHD were divided into stable angina group and acute coronary syndrome group. RHR, risk factors for coronary heart disease and their correlation were analyzed. Results RHR was higher in the acute coronary syndrome group than in the stable angina group （P〈0.01）. Logistic regression analysis showed that RHR （OR =1.052, 95% CI： 1.009-1.097, P=-0.017）, systolic blood pressure （OR=1.027, 95% CI： 1.003-1.053, P=0.031） and hyperglycemia （OR= 2.743, 95% CI： 1.207-6.233, P=0.016） were independent risk factors for acute coronary syndrome. Conclusion RHR is an independent risk factor for incidence of acute coronary syndrome.