5Scarpignato C. Poor effectiveness of proton pump inhibitors in non-erosive reflux disease: the truth in the end [J ]. Neurogastroenterol Motil, 2012,24 (8) : 697-704.
7Wex T, Mnkemialler K, Stahr A, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal eomponems in oesophageal rnucosa[J]. Histopathology, 2012, 60(3) :405-415.
8Namiot Z, Sarosiek J, Rourk RM, et al. Human esophageal secretion:mueosal response to luminal acid and pepsin[J]. Gastroenterology, 1994,106(4) : 973-981.
9Marshall RE. The relationship between acid and bile reflux and symptoms in gastro-oesophageal reflux diease[J]. Gut, 1997, 40(2) : 182-187.
10Malenstein H, Farre R, Sifrim D. Esophageal dilated intercellular spaces (DIS) and nonerosive reflux disease [J]. Van Gastroenterol, 2008,103 (4) : 1021-1028.
6Calabrese C, Fabbri A, Bortolotti M, et al. Dilated intercellular spaces as a marker of oesophageal damage: comparative results in gastro-oesophageal reflux disease with or without bile reflux. Aliment Pharmacol Ther, 2003, 18: 525-532.
7Caviglia R, Ribolsi M, Maggiano N, et al. Dilated intercellular spaces of esophageal epithelium in nonerosive reflux disease patients with physiological esophageal acid exposure. Am J Gastroenterol, 2005, 100: 543-548.
8Fass R , Fennerty MB, Vakil N. Nonerosive reflux disease -current concepts and dilemmas. Am J Gastroenterol, 2001, 96: 303-314.
9Tobey NA, Hosseini SS, Argote CM, et al. Dilated intercellular spaces and shunt permeability in nonerosive acid-damaged esophageal epithelium. Am J Gastroenterol, 2004, 99 : 13-22.
10Bradley LA, Richter JE, Pulliam TJ, et al. The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am J Gastroenterol, 1993, 88 : 11-19.