无肌松药下瑞芬太尼复合异丙酚气管插管的临床观察

Clinical observation on remifentanil combined with propofol in endotracheal intubation without muscle relaxant

目的评价无肌松药下瑞芬太尼复合异丙酚诱导时的气管插管条件。方法拟行气管插管全身麻醉的手术患者60例,ASAⅠ～Ⅱ级。年龄20～55岁,体重52～75kg。随机分为1、2、3组,依次静脉注射异丙酚2mg/kg(>1min)加瑞芬太尼1、2、3μg/kg(>2min)行麻醉诱导进行气管插管条件评分,同时记录诱导及插管过程中不良反应。结果气管插管满意率1、2、3组分别为50%、80%和90%。结论瑞芬太尼2μg/kg复合异丙酚2mg/kg不加用肌松药行气管内插管能提供良好的插管条件,但对心血管系统有轻微抑制。

Objective To evaluate the condition of remifentanil combined with propofol in endotracheal intubation without muscle relaxant.Methods Sixty patients who were given endotracheal intubation and general anesthesia were selected,their ASA was Ⅰ to Ⅱ level,whose age were 20-55 years old,weight were 52-75 kg.They were divided into group 1,2,3,and were given propofol 2 mg/kg（ 1 min） with mainline,remifentanil 1,2,3 μg/kg（ 2 min） successively.The conditions of endotracheal intubation were evaluated;adverse reactions were recorded in the process of induction and intubation.Results The satisfaction rate of group 1,2,3 were 50%,80% and 90% respectively.Conclusion Remifentanil 2 μg/kg combined with propofol 2 mg/kg in endotracheal intubation without muscle relaxant can provide a good condition of endo tracheal intubation,but it has a slight suppression on the cardiovascular system.