摘要
目的探讨本院药物不良反应(ADR)发生的特点、规律,为临床合理用药提供指导依据。方法对本院ADR监测中心收集到的312份ADR报告进行回顾性分析。结果 312例ADR报告中,50~86岁患者ADR发生率最高(52.25%);涉及药物品种29种,以抗感染药物居首位(86.86%);ADR最为常见的临床表现在皮肤及其附件损害(76.28%)。结论 ADR的发生与诸多因素有关,应加强ADR的监测工作,以减少或避免ADR的发生,保障患者用药合理、安全、有效。
Objective To study the features, general patterns of adverse drug reaction(ADR) occurred in our hospital and to provide the guidance basis for rational use of drugs in clinic. Methods The data of 312 cases of ADR from the center of ADR monitor were analyzed retrospectively and statistically. Results In 312 ADR cases, patients between 50 to 86 years old age accounted for 52.25% in the first place; the drugs that induced ADR totaled 29 kinds, with anti-infectives showing the highest proportion (86.86%); the main manifestation of the ADR was lesions of skin and its appendages (76.28%). Conclusion The occurrence of ADR is affected by many factors. Therefore, we should strengthen the monitoring of ADR in order to reduce or avoid ADR, and to use reasonable safe and effective medications.
出处
《中国当代医药》
2012年第34期145-146,共2页
China Modern Medicine
关键词
不良反应
抗菌药物
报告
分析
Adverse drug reaction
Antibacterials
Report
Analysis