妊娠期哺乳期乳腺癌诊治分析

The analysis of diagnosis and treatment of breast cancer during pregnancy and lactation

目的分析妊娠期及哺乳期乳腺癌的诊断、治疗和预后。方法通过10例临床资料分析,结合有关文献。结果妊娠期乳腺癌在终止妊娠后5年生存率为25%,哺乳期乳腺癌的5年生存率为66.7%。治疗原则同一般乳腺癌,依据临床分期、妊娠周数及患者对胎儿的需要程度。结论妊娠期乳腺癌临床表现与普通乳腺癌相同,但临床诊断更晚,妊娠期乳腺癌5年生存率差,终止妊娠并不能提高患者生存率;确诊主要靠细胞学穿刺或活检。

Objective To analyze the diagnosis, treatment and prognosis of breast cancer during pregnancy and lactation. Methods The diagnosis and treatment for 10 cases of breast cancer during pregnancy and lactation were retrospectively evaluated combining with related literature. Results The 5-years survival rate of termination of breast cancer during pregnancy were 25%, the 5-years survival rate of lactating breast cancer were 66.7%. The treatment principle of breast cancer during pregnancy and lactation was not different from ordinary breast cancer, according to the tumor, stage, gestational age and the desire for fetus. Conclusion The later clinical manifestations in breast cancer patients during pregnancy is the same as ordinary breast cancer. Pregnancy associated breast cancer is mostly at later stage in the time of diagnosis and has poorer survival rate than ordinary breast cancer. Breast cancer during pregnancy 5 years survival rate is poor, termination of pregnancy does not improve survival rate. The diagnosis is made through fine needle biopsy or lumpectomy.