普罗帕酮与胺碘酮转律阵发性室上性心动过速43例疗效分析

The clinical effect of propafenone and amiodarone on the patients of paroxysmal supraventricular tachycardia(PSVT)plus 43 cases report

目的比较静脉注射普罗帕酮与胺碘酮转律阵发性室上性心动过速的疗效。方法将43例阵发性室上性心动过速患者随机分为普罗帕酮组和胺碘酮组,分别静脉注射普罗帕酮70～140 mg和胺碘酮150～300 mg,观察室上性心动过速的转律情况。结果普罗帕酮组21例,转复成功17例(81.0%);胺碘酮组22例,转复成功18例(81.8%),2组比较无显著性差异(P>0.05)。转律成功时间:普罗帕酮组(24.2±19.5)min,胺碘酮组(40.5±18.5)min,2组比较差异显著(P<0.05)。结论普罗帕酮与胺碘酮急诊转律阵发性室上性心动过速均有显著疗效,但普罗帕酮转律时间更短,对于无基础心脏病或心功能正常患者,可作为急诊首选药物。

Objective To explore the clinic curative effect of propafenone hydrochloride injection and amiodarone hydrochloride injection on the patients of PSVT.Methods 43 patients of PVST were divided into propafenone group and amiodarone group.intravenous respectively propafenone 70-140mg or amiodarone 150-300mg,observe the effect of heart beat recovery.Results There were 17case success in propafenone group of 21 case,the termination rate is 81.0%.There were 22 case success in amiodarone group of 22 case.The termination ratewas 81.8% and no significant difference between two groups（P0.05）.The time of heart beat recovery in Propafenone group were（24.2±19.5） min and Amiodarone group were（40.5±18.5） min,there was significant difference of the time between the two groups Conclusion Propafenone and Amiodarone treatmen are both effective on PSVT.