温阳健脾法联合西药治疗2型糖尿病胰岛素抵抗阳虚证的疗效观察

The observation of the efficacy for warming yang and strengthening spleen method combined with western medicine in the treatment of type 2 diabetic insulin resistance with yang deficiency syndrome

目的探讨温阳健脾法联合西药治疗2型糖尿病胰岛素抵抗阳虚证的疗效。方法选取2010年3月～2012年7月于本院采用西药进行治疗的45例2型糖尿病胰岛素抵抗阳虚证患者为对照组,同期的45例采用温阳健脾法联合西药进行治疗的患者为观察组,后将两组患者的治疗总有效率及治疗前后的空腹血糖(FBG)、餐后2h血糖(2hPG)、胰岛素敏感指数(ISI)、空腹胰岛素(FINS)及餐后2h胰岛素(2hINS)进行比较。结果观察组的治疗总有效率明显高于对照组,而治疗后4周及8周FBG、2hPG、FINS及2hINS均低于对照组,ISI高于对照组,差异均有统计学意义(P<0.05)。结论温阳健脾法联合西药治疗2型糖尿病胰岛素抵抗阳虚证的疗效优于单纯西药治疗的效果。

Objective To investigate the efficacy of warming yang and strengthening spleen method combined with western medicine in the treatment of type 2 diabetic insulin resistance with yang deficiency syndrome. Methods Forty five patients of type 2 diabetic insulin resistance with yang deficiency syndrome in our hospital from March 2010 to July 2012 were chosen as the control group, who treated by western medicine for treatment. 45 cases over the same period using the warm- ing yang and strengthening spleen method combined with western medicine for treatment were set as the observation group. The total efficiency of treatment and FBG, 2hPG, ISI, FINS and 2bINS for the two groups before and after the treatment were compared. Results The total efficiency of the observation group was significantly higher than the control group. The FBG, 2hPG FINS and 2bINS 4 weeks and 8 weeks after treatment were lower than the control group, the ISI was higher than that in the control group, there were significant differences （P 〈 0.05）. Conclusion The clinical efficacy for warming yang and strengthening spleen method combined with western medicine in the treatment of type 2 diabetic insulin resistance with yang deficiency is superior to the effect of western medicine alone.