垂体生长激素腺瘤的MRI特点

MRI characteristics of pituitary growth hormone adenoma

目的:探讨垂体生长激素(GH)腺瘤的MRI特点。方法:回顾性分析垂体瘤98例,其中GH腺瘤51例,微腺瘤18例,大腺瘤33例;非GH腺瘤47例,微腺瘤18例,大腺瘤29例,术后病理证实为泌乳素(PRL)腺瘤。患者均行垂体MRI平扫,71例患者行增强检查。评估腺瘤在MRI上的形态、信号特点及向周围侵犯情况。结果:GH腺瘤T2WI上呈等或低信号,较少囊变坏死。GH微腺瘤易使鞍底下陷,大腺瘤与PRL大腺瘤一样向周围生长,但多向下突入蝶窦。部分GH腺瘤患者可见颅骨板障增厚。结论:GH腺瘤T2WI上呈等或低信号,较易向下生长。

Objective： To evaluate the MRI characteristics of pituitary growth hormone （GH） adenomas. Methods： A retrospective anal- ysis was done in 98 cases of pituitary tumors confirmed,including 51 GH adenomas, and non-growth hormone （non-GH） adenomas. A- mong GH adenoma,18 cases were microadenomas and 33 cases were macroadenoma. Among non-GH adenomas, 18 cases were mi- croadenomas, 29 cases were macroadenoma which were diagnosed prolactin （PRL） adenoma by postoperative pathologic. All the patients underwent pituitary MRI scan and 71 cases underwent enhanced MRI. MRI form of adenoma signal intensity and the surrounding exten- sion were assessed. Results：GH adenomas were usually from hypointense to isointense on T2-weighted images. Cystic and necrotic were less common in GH adenomas. GH microadenomas was easier to perforate the floor of the sell. In term of extension, there was no differ- ences on the suprasellar and parasellar （left and right） extension.There was differences on the infrasellar extension, GH macroadenomas had a higher level. Skull diploe increased thickness in some of the patients with GH adenomas. Conclusion： GH adenomas are from hy- pointense to isointense on T2-weighted images and tended to infrasellar extension.