艾滋病合并马尔尼菲青霉菌病肝脾B超表现分析

Manifestations of ultrasound images of liver and spleen in patients of AIDS complicated with penicilliosis marneffei

目的分析艾滋病(AIDS)合并马尔尼菲青霉菌病(PSM)后肝脾B超表现。方法对102例AIDS合并PSM(观察组)以及同期102例AIDS不合并PSM患者(对照组)的肝脾超声图像资料进行对比分析。结果肝右叶斜径、肝门脉主干径、脾脏厚度的均值观察组分别为(140.13±14.15)mm、(10.51±1.22)mm、(41.48±9.51)mm,对照组分别为(135.91±12.34)mm、(10.86±1.19)mm、(37.77±8.71)mm,两组比较差异有统计学意义(P<0.05或P<0.01);脾肿大、肝脾均肿大、脂肪肝声像检出率观察组分别为54.90%、45.10%、45.10%,对照组分别为40.20%、27.45%、10.78%,两组比较差异有统计学意义(P<0.05或P<0.01)。结论 AIDS合并PSM患者发生肝脾肿大和脂肪肝病变率较高,肝脾肿大和脂肪肝是艾滋病合并PSM特征之一。

Objective To analyze the manifestation of ultrasound images of liver and spleen in patients of AIDS complicated with penicilliosis marneffei （PSM）. Methods The ultrasound images of liver and spleen in 102 ca- ses of AIDS comlicated with PSM （treatment group） and 102 patients of AIDS without PSM （control group） in the same period were analyzed retrospectively. Results Ultrasonography showed that the oblique diameter of right liver lobe, diameter of hepatic portal vein and thickness of the spleen （mean） were （140.13 ± 14. 15 ）mm, （10. 51 ± 1.22 ） mm, （41.48 ± 9.51 ）mm respectively in the treatment group, and （ 135.91 ± 12. 34 ） mm, （ 10. 86 ± 1.19 ） mm, （37.77±8.71 ）mm respectively in the control group, there were statistically significant differences between two groups （P 〈 0. 05 or P 〈 0.01 ）. The rate of splenomegaly, hepatosplenomegaly and fatty liver were 54. 90%, 45.10% ,45.10% respectively in the treatment group, and 40.20% ,27.45% , 10. 78% respectively in the control group. There were significant differences between two groups （ P 〈 0. 05 or P 〈 0.01 ）. Conclusion The rates of hep- atosplenomegaly and fatty liver are higher in the patients of AIDS complicated with PSM. Hepatosplenomegaly and fat- ty liver are one of features in patients with AIDS complicated with PSM.