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促进真皮替代物血管化进程的因素

Advance of Revascularization of Dermal Substitutes after Prefabrecation
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摘要 对于严重大面积烧伤患者,自体皮肤组织移植常难以实施。尽管真皮替代物以其优良的理化特性,在烧伤重建外科领域发挥了重大作用,但与传统皮片移植相比,仍存在着血管延迟长入真皮层的缺陷。本文就真皮替代物的特性,以及移植后血管化进程的促进因素进行综述。 It is really difficult to launch the autologous skin grafting when facing severely burned patients with large skin defects. Regardless of the splendid physicochemical and biochemical characteristics of dermal substitute in burns and reconstructive surgery, a manifest drawback of current dermal substitutes technologies is the apparent delay in vascular ingrowth compared with conventional skin grafts. The characteristics and factors accelerating the revascularity of dermal substitutes after transplantation were reviewed.
作者 周显玉 杨军
机构地区 上海交通大学医学院附属第九人民医院整复外科
出处 《组织工程与重建外科杂志》 2012年第6期344-348,共5页 Journal of Tissue Engineering and Reconstructive Surgery
基金 上海市科委科研计划项目(10411964200)
关键词 真皮替代物 血管生成 细胞因子 干细胞 基因介导载体 Dermal substitute Revascularity Cytokines Stem cells Gene-mediated carrier
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献62

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二级参考文献45

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组织工程与重建外科杂志
2012年 第6期

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