51例2型糖尿病患者血脂分析

Lipid analysis of 51 patients with type 2 diabetes

目的:探讨2型糖尿病患者血脂紊乱的特点及2型糖尿病患者合并血脂异常患病率。方法:通过对51例2型糖尿病患者的血脂测定,包括:总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C),并与正常对照组进行统计学分析。结果:2型糖尿病患者血脂异常表现甘油三脂(TG)、低密度脂蛋白(LDL-C)升高,差异有统计学意义(P<0.01);高密度脂蛋白(HDL-C)降低,差异有统计学意义(P<0.01);总胆固醇(TC)升高,差异无统计学意义(P>0.05)。2型糖尿病患者合并血脂异常患病率为52.94%。结论:2型糖尿病患者易引起血脂代谢紊乱合并高脂血症,可能是2型糖尿病患者易并发心脑血管疾病的重要原因。

Objective： To investigate the characteristics of dyslipidemia in patients with type 2 diabetes and the prevalence of type 2 diabetes patients with complication of abnormal hyperlipidemia. Methods： lipids were measured in 51 patients with type 2 diabetes, including： total cholesterol （TC）, triglyceride （TG）, high densi- ty lipoprotein （HDL-C）, low-density lipoprotein （LDL-C）, and statistical analysis was carried out with the normal control group. Results： Blood lipid of patients with type 2 diabetes showed abnormalities, with triglyc- eride （TG）, and low-density lipoprotein （LDL--C） elevated, P 〈 0.01, significant difference; while high- density lipoprotein cholesterol （HDL--C） reduced, P 〈 0.01. The difference was statistically significant; and total cholesterol （TC） elevated, P 〉 0. 05, the difference was not statistically significant. The prevalence of Type 2 diabetic patients with dyslipidemia was 52.94%. Conclusion：It is easy for Type 2 diabetes to suffer from dyslipidemia combined with hyperlipidemia, which might account for occurrence of the complications of cardiovascular and cerebrovascular diseases for type 2 diabetes.