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NGF对神经干细胞内Mash1表达的影响 被引量：3

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摘要 目的:以Mash1为切入点,深入研究NGF反应性NSCs向胆碱能神经元分化过程中的机制。方法:取体外培养传至第三代的神经干细胞,在含不同浓度NGF的神经干细胞分化培养基中进行分化诱导,采用RT-PCR法测定诱导后Mash1的mRNA相对表达水平。结果:各实验组均有Mash1的表达,其中空白对照组表达最少,以NGF100mg/L组表达量最高。结论:NGF能够促进NSCs内Mash1的表达。
作者 王克健 孙光涛 黄昕艳
机构地区 佳木斯大学附属第一医院神经内四科 佳木斯大学附属第二医院神经内科
出处 《黑龙江医药科学》 2012年第6期56-57,共2页 Heilongjiang Medicine and Pharmacy
基金 佳木斯大学研究生创新资助项目 编号:YJSCX2011-020JD
关键词 神经干细胞 胆碱能神经元 神经生长因子 Mash1
分类号 Q42 [生物学—神经生物学] Q786 [生物学—分子生物学]
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参考文献5

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二级参考文献9

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共引文献12

同被引文献20

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  • 9张春斌,谈西满,罗佳滨,胡玉红,常春艳,张玉萍,刘爽.子宫内膜异位症动物模型的研究现状及进展[J].黑龙江医药科学,2008,31(3):80-81. 被引量：8
  • 10卢邦春,黄秀峰,周彩云,许泓,林俊,张信美.子宫腺肌病患者子宫内膜神经纤维的分布及其临床意义[J].中华妇产科杂志,2009,44(5):324-327. 被引量：8

引证文献3

二级引证文献13

黑龙江医药科学
2012年 第6期

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