玉溪市人民医院抗菌药物使用强度分析及干预管理

Analysis and Intervention Management of Antibacterial Use Density in The People's Hospital of Yuxi

目的分析玉溪市人民医院抗菌药物使用情况,为合理使用抗菌药物提供参考依据.方法根据玉溪市人民医院计算机中心提供数据计算出玉溪市人民医院抗菌药物消耗量,以限定日剂量(DDD)为单位,分别计算2010年、2011年抗菌药物使用强度(AUD)并进行分析.结果玉溪市人民医院2010年、2011年AUD分别为80.77 DDD/100人/d、64.37 DDD/100人/d.在这2 a中,二代头孢AUD最高,其次为三代头孢(含复方制剂)、硝基呋喃类及喹诺酮类抗菌药物.结论玉溪市人民医院抗菌药物应用存在AUD高、三代头孢及喹诺酮类使用率高、联合用药率高等问题.应采取干预措施,加强抗菌药物合理应用宣传培训,严格掌握三代头孢及喹诺酮类抗菌药物的临床适应症,控制玉溪市人民医院抗菌药物使用强度,促进抗菌药物合理应用.

Objective To provide an evidence for rational use of antibacterials in the clinic through analyzing the antibacterial use in our hospital.Methods By retrospective study,the data of drug used between 2010 and 2011 were collected and analyzed by Excel 2003.Taking defined daily dose（DDD）as the unit,antibacterial use density（AUD） was calculated and analyzed.Results The AUD in 2010 and 2011 was 80.77 and 64.37 DDD every 100 patients per day,respectively.In these two years,the hightest AUD was the second generantion of cephalosporin,and then the third generantion of cephalosporin（including compound preparation）,Nitrofurans and quinolone antibacterials.Conclusions The problems in application of antimicrobials are high AUD,frequent use of the three generation cephalosporin and quinolones,and high joint usage rate.We should take intervention measures to strengthen advocating reasonable application of antibacterials,strictly grasp the clinical indications of three generations of cephalosporin and quinolone antibacterials,control AUD,and promote the reasonable application of antibacterials.