肺泡蛋白沉积症的X线及CT表现

X-ray and CT Imaging Manifestations of Pulmonary Alveolar Proteinosis

目的探讨肺泡蛋白沉积症(PAP)的X线和CT影像学表现,以提高对肺泡蛋白沉积症的认识和诊断水平.方法回顾性分析4例经病理及肺泡灌洗证实的肺泡蛋白沉积症患者X线和CT影像学特点.结果X线片和CT表现为双肺对称或不对称分布的磨玻璃样阴影,CT能更清楚地显示磨玻璃中的网格状影(铺路石征)和充气支气管征.结论 CT可以更清晰显示PAP的病变范围和程度,并且具有典型影像学表现,CT可作为PAP首选的诊断方法,X线片对判断病情也有价值.

Objective To explore the X-ray and CT manifestations of the pulmonary alveolar proteinosis（PAP）and to improve the accuracy of the diagnosis.Methods The imaging data of 4 cases of pulmonary alveolar proteinosis confirmed by pathology or bronchoalveolar lavage were retrospectively reviewed.The imaging features were investigated.Results Both of the chest radiography and CT presented symmetrical or asymmetrical diffuse ground glass opacity.CT imaging was better to show reticular shadows of ground glass opacity（crazy-paving sign） and air bronchogram.Conclusion CT can clearly demonstrate the extent of PAP and has typical imaging features,which can be used as preferred diagnostic method.The chest radiography is of value in evaluation of PAP.