摘要
目的观察小剂量美罗华治疗免疫性血小板减少症(ITP)的疗效.方法选择ITP患者20例,用小剂量美罗华治疗(剂量为100 mg/次,每周1次,连续4周),观察血小板计数及不良反应.结果总反应率(OR)和完全反应率(CR)分别为70%,95%CI 45.8%～88.1%和45%,95%CI 23.2%～68.6%,中位反应时间为38(16～92)d.结论小剂量美罗华可作为对常规治疗无效患者一种有效的治疗.
Objective To evaluate the efficacy of low-dose rituximab on immune thrombocytopenia（ITP）.Method Twenty patients were given 100mg rituximab weekly for four weeks,the platelet count and adverse events were observed.Results Overall and complete response（OR and CR）rates were 70% and 45%,respectively.The median time to response was 38（16-92） day.Conclusion The low-dose rituximab regimens（100 mg weekly for four weeks）is effective for patients with ITP.
出处
《昆明医科大学学报》
CAS
2012年第11期99-101,共3页
Journal of Kunming Medical University
关键词
小剂量
美罗华
疗效
免疫性血小板减少症
Low-dose
Rituximab
Treatment efficacy
Immune thrombocytopenia
