中国1950～2010年鼠疫患者性别构成比分析

Sex constituent ratio of plague patients in China from 1950 to 2010

目的了解不同疫源地我国鼠疫患者性别构成情况,探讨年龄、病型、感染方式、病死率等与鼠疫患者性别构成的关系。方法收集1950～2010年全国鼠疫个案资料,用卡方检验和二项分布检验等方法对鼠疫患者性别构成情况进行分析。结果旱獭疫源地男性病例明显多于女性(P<0.01);分年龄组比较,只有20～39岁年龄组鼠疫患者男女比例存在差异(P<0.01);通过接触人(P<0.05)和旱獭(P<0.01)感染的病例男女比例差别有显著性;患腺型(P<0.05)和肺型(P<0.01)鼠疫的男性病例也多于女性;病死率则与性别无关(χ2=1.175,P>0.05)。结论人类感染鼠疫与性别关系不大,只与不同性别人群接触病原体机会的多寡和接触部位有关。

Objectives To know the sex composition of plague patients in different endemic focuses and the correlation between age,disease type,source of infection and mortality.Methods The plague case data in China from 1950 to 2010 were collected,chi-square test and binomial test were used in sex constituent ratio analysis.Results The male cases were obviously higher than female cases in the plague focus of marmot（P〈0.01）.There was difference in sex composition from 20 to 39 years old（P〈0.01）,and contacting people（P〈0.05） and marmot（P〈0.01）.The male cases infected glandular plague（P〈0.05） and pneumonic plague（P〈0.01） were higher than female.Mortality had no relationship with sex（χ^2= 1.175,P〈0.05）.Conclusion Sex difference does not matter much on plague infection,but contacting with pathogen and contact parts matters much.