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预注射喷他佐辛对预防小儿七氟醚吸入麻醉后躁动的临床观察 被引量:2

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摘要 目的探讨术前预注射喷他佐辛对预防小儿七氟烷麻醉苏醒期躁动的效果及安全性。方法择期全麻下行唇腭裂修复手术的患儿40例,ASAⅠ~Ⅱ级,年龄1~3岁。随机分为喷他佐辛(P组)和对照组(C组),每组20例。麻醉诱导采用潮气量法,起始刻度为8%,回路预充,给患儿吸入七氟醚混合气体,直至患儿睫毛反射消失、下颌松弛后,经口异型管气管插管。气管插管后P组静脉注射喷他佐辛(0.15mg/kg)5ml,C组静脉注射生理盐水5mL,根据患儿生命体征调整吸入浓度,稳定吸入七氟醚在0.8~1.2MAC,氧流量2 L/min维持麻醉。采用浓度递减洗出法排出七氟醚。符合拔管指征后拔除气管导管。拔管后进入麻醉恢复室进行苏醒期躁动评分。结果 P组苏醒期躁动率明显低于C组(P<0.05);P组拔管时间明显延长(P<0.05),但2组患儿转出麻醉恢复室时间差异无统计学意义(P>0.05)。结论术前预注射喷他佐辛可降低小儿七氟烷麻醉苏醒期躁动的发生率,对提高小儿七氟烷麻醉围术期安全更有意义。
出处 《河北医科大学学报》 CAS 2012年第12期1464-1466,共3页 Journal of Hebei Medical University
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