无锡市锡山区健康检查人群高尿酸血症的患病情况

Prevalence of hyperuricemia among physical examination population in Xishan District of Wuxi City

目的通过了解无锡市锡山区健康检查人员血尿酸水平与性别、年龄的关系,为防治高尿酸血症(HUM)提供依据。方法采用酶法对2010—2011年12 559名来我中心进行健康检查的人员进行血尿酸检测分析。结果 12 559名健康人群中HUM患病率为15.00%。其中男为19.18%,女为6.69%,男性明显高于女性(χ2=342.57,P<0.01)。2010年总HUM患病率为15.77%,2011年总患病率为12.34%,差异有统计学意义(χ2=20.19,P<0.01)。20岁及以下年龄组患病率最高为17.24%,以后逐年龄组下降,至40岁及以上年龄组又有回升至14.50%,各年龄组间差异均有统计学意义(χ2=63.85,P<0.01)。结论应对健康人群进行HUM相关知识的普及,定期检测血尿酸,有效预防和减少HUM的患病率。

[Objective]To understand the relationship between the level of serum uric acid and gender,age among physical examination population in Xishan District of Wuxi City,provide the basis for the prevention and treatment of hyperuricemia（HUM）.[Methods]The levels of serum uric acid in 12 559 people received the physical examination in Xishan CDC during 2010-2011 were tested and analyzed by enzymatic method.[Results]Among 12 559 healthy people,the HUM prevalence was 15.00%.The HUM prevalence in males（19.18%） was higher than that in females（6.69%） significantly（χ2=342.57,P0.01）.The total HUM prevalence in 2010 and 2011 was 15.77% and 12.34% respectively,and the different was significant（χ2=20.19,P0.01）.The HUM prevalence in 20 year-old and below age group was the highest（17.24%）,then the prevalence decreased with increasing age,but that in 40 year-old and above age group resumed to 14.50%,and there was significant difference among different age groups（χ2=63.85,P0.01）.[Conclusion]It is essential to carry out the education of HUM knowledge among healthy population and regularly detect the level of serum uric acid,to effectively reduce HUM prevalence.