胺碘酮与利多卡因治疗急性心肌梗死伴持续性室性心动过速的疗效观察

Observation on effect of amiodarone and lidocaine in treating acute myocardial infarction complicating sustained ventricular tachycardia

目的探讨胺碘酮与利多卡因治疗急性心肌梗死(AMI)伴持续性室性心动过速(室速)的临床效果。方法回顾性分析AMI伴持续性室速患者的临床资料,分为胺碘酮组和利多卡因组,评估两种药物抗心律失常的效果。结果胺碘酮组总有效率为87.09%,利多卡因组为54.54%,两组比较,差异有统计学意义(P<0.05)。而两组短期不良反应比较,差异无统计学意义。结论胺碘酮治疗AMI伴持续性室速的临床效果好,安全性高,值得推广应用。

Objective To investigate the effect of amiodarone and lidocaine in treating acute myocardial infarction（AMI） complicating sustained ventricular tachycardia.Methods The clinical data in the cases of AMI complicating sustained ventricular tachycardia were retrospectively analyzed.The cases were divided into the amiodarone group and the lidocaine group.The antiarrhythmic effects of two drugs were evaluated.Results The total effective rate was 87.09% in the amiodarone group and 54.54% in the lidocaine group with statistical difference between them（P〈0.05）.The short term adverse reactions had no statistical difference between the two groups.Conclusion Amiodarone has good effect and high safety in treating AMI complicating sustained ventricular tachycardia,and deserves to be promoted.