摘要
呼吸道黏膜免疫系统作为黏膜免疫系统的一部分,是保护机体特别是呼吸道免受病原体侵犯的重要屏障。研究表明,慢性阻塞性肺病、哮喘、肺结核等呼吸系统疾病均存在黏膜免疫功能异常。通过"肺开窍于鼻"、"肺与大肠相表里"和"培土生金"等论,学者们探讨了中医药影响呼吸道黏膜免疫系统功能的可行性,并通过动物实验和临床研究发现,中医药治疗可以修复受损的支气管黏膜结构,提高呼吸道局部免疫功能。其机制尚需要进一步深入研究。
Respiratory passage mucosa immune system is a part of the mucosal immune system,which is the important protective screen to protect the body against the pathogen.Researches showed that mucosal immune dysfunction occurred in the respiratory diseases such as COPD,asthma and pulmonary tuberculosis etc.By using the theory of 'the nose being the orifice of the lung','the lung and the large intestine are interior-exteriorly related','strengthening earth(spleen) to generate metal(lung)',researchers studied the feasibility of using TCM to affect the function of respiratory passage mucosa immune system.On the base of the animal experiments and clinicl studies,they found that TCM could repair the damaged bronchial mucosal structure,improve the local immunologic function of respiratory passage.The mechnism needs to be further investigated.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2013年第1期164-167,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金面上项目(No.81072767)~~
关键词
呼吸道黏膜免疫
肺开窍于鼻
肺与大肠相表里
培土生金
Respiratory passage mucosa immunization
Nose being the orifice of the lung
Lung and the large intestine are interior-exteriorly related
Strengthening earth(spleen) to generate metal(lung)