血小板减少及血液中微粒的临床检验分析

The Clinical Examination Analysis of Thrombocytopenia and the Particles in Blood

目的:对血小板减少及血液中微粒的临床检验情况进行分析探讨。方法:随机抽取2010年1月-2012年8月临床部分收治的冠心病、急性脑梗死、慢性肾功能衰竭、急性白血病化疗后及健康体检者作为研究对象,对其分别采用流式细胞仪,以3mm、0.8mm的标准微球作内参对照展开血小板微粒检测,并对比分析检测结果。结果:冠心病、急性脑梗死、慢性肾功能衰竭者血浆中血小板微粒显著高于健康者(P<0.05),而急性白血病化疗后患者血小板微粒增加不明显,与健康者比较差异无统计学意义(P>0.05)。结论:血小板微粒能够作为对血小板活化、预测和诊断血栓性疾病的一项重要指标,值得关注。

Objective： To discuss the clinical examination situation of thrombocytopenia and the particles in blood.Methods： Randomly selected clinical patients with coronary heart disease, acute cerebral infarction, chronic renal failure, acute leukemia after chemotherapy and health physical examination person in January 2010 to August 2012 as the research object, which respectively by flow cytometry instrument, to 3 mm, 0.8 mm standard microspheres for control on platelet particle detection, and a comparative analysis of the test results.Results： The platelets particles in the blood in patients with coronary heart disease, acute cerebral infarction, chronic renal was significantly higher than healthy patients（P〈0.05）, and acute leukemia patients after chemotherapy increased platelet particles was not apparent, and health patients of comparisons difference nonsense （P〉0.05）.Conclusion： Platelet particles as an important index of platelet activation, forecast and diagnosis of thrombotic diseases is worth attention.