重度子痫前期并发胎儿生长受限相关性探讨

STUDY ON RISK FACTORS OF SEVERE PRE-ECLAMPSIA CONCURRENT FGR

目的探讨重度子痫前期并发胎儿生长受限(FGR)的相关因素。方法选择2007年4月—2009年4月在我院产科分娩的57例重度子痫前期单胎患者,按新生儿出生体重分为FGR组(A组)含小于胎龄儿和非FGR组(B组)含非小于胎龄儿。对二组中重度子痫前期患者监测指标进行分析,寻找重度子痫前期并发胎儿生长受限的相关因素。结果 A组中发病孕龄、分娩孕龄、1minApgar评分明显低于B组,差异有统计学意义(P<0.05);A组中血压高、眼底异常严重程度、羊水过少改变、24h尿蛋白定量明显高于B组,差异有统计学意义(P<0.05)。结论重度子痫前期患者并发FGR的主要危险因素是发病孕周和24CTP及高血压严重程度,积极防治,可改善母儿结局。

Objective To discuss the related factors of severe pre- eclampsia complicated with fetal growth restriction. Methods Total 57 singleton pregnancies patients with severe pre- eclampsia from A- pril 2007 to April 2009 in author＇s hospital were divided into FGR group（A） and non- FGR group（B）ac- cording to birth weight. Some monitoring indicators were analyzed for all patients, then look for the rele- vant factors of severe preeclampsia complicated by fetal growth restriction. Results The gestational age, birth gestational age and one minute Apgar score in group A were significantly ldwer than group B（P〈 0.05）. The incidence of high blood pl^essure, severity of retinal abnormalities, oligohydramnios, 24 - hour urinary protein in group A were significantly higher than group B（P〈0. 05）. Conclusion The major risk factors for patients with severe pre- eclampsia complicated by FGR are the severity of high blood pressure, gestational age and 24CTP. It is important for improving the maternal and fetal outcomes to take soma posi- tive control steps.