机械通气在救治危重肺源性心脏病呼吸衰竭患者中的疗效观察

Clinical efficacy of Mechanical Ventilation in the Treatment of Critical Pulmonary Heart Disease Patients with Respiratory Failure

目的:探讨将机械通气应用于危重肺源性心脏病呼吸衰竭患者的救治中的临床疗效及应用价值。方法:回顾性分析近三年我院收治的危重肺源性心脏病呼吸衰竭患者143例,其中有53例患者采用针对肺源性心脏病的药物治疗(对照组),90例患者在对照组治疗方法的基础上采用机械通气治疗(通气组),对比两组的治疗效果。结果:治疗两周后,通气组患者的PaO2、pH显著高于对照组,P<0.01;而HR、PaCO2及住院天数显著降低,P<0.01。对照组和通气组患者在治疗1d后肺功能(FEV1)改善情况无统计学差异,P>0.05;通气组患者在治疗3d、7d及2周后肺功能(FEV1)改善情况显著优于对照组,P<0.05。结论:对重症肺源性心脏病呼吸衰竭患者采用机械通气救治是有效的较安全的。

Objective： To investigate the clinical efficacy of mechanical ventilation used in critical pul- monary heart disease （ PHD ） patients with respiratory failure and explore its clinical application value. Meth- od： 143 critical PHD patients with respiratory failure were collected and retrospectively analyzed in our hos- pital. 143 cases of patients were lvided into normal treatment control group（ n=53 ） and mechanical ventila- tion treatment group （n = 90 ）. The clinical efficacy was compared between the two groups. Result： After treated for 2 weeks, the value of PaO2 , pH were significantly higher in ventilation group than that in control group（ P〈0.01 ）. However, the HR, PaCO2, and hospital stay were significantly lower in ventilation group than that in control group{ P〈0. 01）. After treated for one day, No significant change of lung function （ FEV1 ） was found between the two groups（ P〉0.05 ）. After treated for 2 days, 7 days, or 3 weeks, the change of FEV1 was better in ventilation group than that in control group（P〈0.05）. Conclusion： It is ef- fective and safer of critical PHD patients with respiratory failure to treat with mechanical ventilation.