养阴生肌散对患者压疮部位微生物的抑菌作用探讨

Bacteriostatic Activity of YangYin ShengJiSan on Pressure Sore of Patients

目的:观察中药养阴生肌散对压疮患者压疮部位微生物的抑菌作用。方法:采用琼脂扩散法分别研究养阴生肌散和安尔碘对压疮部位部分革兰氏阳性菌和部分革兰氏阴性菌的抑菌效果,37℃培养24小时,量取槽边缘抑菌区的距离。结果:革兰氏阳性菌(G+)亚组之间差异不具有统计学意义(P>0.05);革兰氏阴性菌(G-)亚组之间差异具有统计学意义(P<0.05);金黄色葡萄球菌、表皮葡萄球菌和类肠杆菌亚组两者之间差异有统计学意义(P<0.05);大肠杆菌和产气肠杆菌亚组两者之间差异有统计学意义(P<0.05)。结论:养阴生肌散对部分G+、G-具有一定的抑制作用。

Objective： To observe bacteriostatic effects of YangYin ShengJiSan on pressure sore of patients. Method： Bacteriostatic effects of YangYin ShengJiSan and AnErDian on Gram-positive bacteria and parts of Gram-negative bacteria found on the pressure sore were investigated respectively with agar diffusion method. Bacteria were cultivated for 24hours at 37℃ and the distance of inhibition zone was measured. Result： The difference between Gram-positive bacteria subunits didn＇t show statistical meaning （P〉0.05）; the difference between Gram-negative bacteria subunits demonstrated statistical meaning （P〈0.05）; the differences among the subunits of staphylococcus aureus, staphylococcus epidermidis and bacillus coli suggested statistical meaning （P〈0.05）; the difference between the subunits of bacillus coli and enterobacter aerogenes suggested statistical meaning （P〈0.05）. Conclusion：YangYin ShengJiSan shows certain inhibition to Gram-positive and Gram-negative bacteria.