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女性原发乳腺神经内分泌癌的临床病理分析

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摘要 目的探讨原发乳腺神经内分泌癌的临床病理特点。方法从2 116例乳腺癌手术标本中,经光镜观察病理形态及免疫组化检测神经内分泌标志物筛出13例乳腺神经内分泌癌,进行临床病理分析并随访。结果患者中位年龄40岁,影像学BI-RADS 1级、2级、3级和4级分别是1例、3例、7例和2例。肿瘤最大径0.2~5.5 cm,临床分期Ⅰ期6例,Ⅱ期7例,其中3例有淋巴结转移。免疫分型8例为Luminal A型,4例为Luminal B型,1例为Basal-like型。术后随访14~60个月,均存活。结论早期多项检查是乳腺神经内分泌癌患者年龄较低原因之一,其免疫表型可能与预后相关,早期诊断预后可能较好。
出处 《广东医学》 CAS CSCD 北大核心 2012年第23期3573-3575,共3页 Guangdong Medical Journal
基金 广东省科技计划项目(编号:2010B060900060) 广东省医学科研基金资助项目(编号:B2008009 A2009086 A2011070)
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