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成比例辅助通气和压力支持通气在运动状态下呼吸力学改变的比较 被引量:7

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摘要 目的探讨不同运动状态下的正常人应用成比例辅助通气(PAV)和压力支持通气(PSV)时受试者呼吸力学的改变,从而为确定临床上慢性阻塞性肺部疾病(COPD)患者进行肺康复锻炼目标及应用无创通气时模式选择提供参考依据。方法观察7名健康成人在不同运动负荷(轻度负荷、中度负荷、亚极限运动状态、极限运动状态)下,在自主呼吸(SB)及不同辅助通气模式(成比例辅助通气、压力支持通气)下,受试者的跨膈压(Pdi)、压力时间乘积(iPTP)、总做功(Wtot)、受试者自身做功(Wp)等呼吸力学参数的变化。结果与自主呼吸比较,7名受试者均感觉在运动状态下PAV优于PSV。随运动负荷增加,SB、PAV和PSV状态下,受试者的Pdi、呼吸做功、iPTP均进行性上升。与SB比较,PAV和PSV均能够降低运动过程中的Pdi、呼吸做功和iPTP(各运动状态下P<0.05),亚极限运动及极限运动状态下PAV的作用优于PSV(P<0.05)。结论轻中度运动量时,PSV及PAV均能有效减少其呼吸做功,但亚极限负荷及极限负荷运动状态时,PAV减少呼吸做功的作用明显优于PSV。
出处 《广东医学》 CAS CSCD 北大核心 2012年第24期3757-3759,共3页 Guangdong Medical Journal
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参考文献9

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