肺癌患者血栓弹力图检测的临床意义

The Clinical Significance of Thrombelastogrophy of Lung Cancer

目的 应用血栓弹力图 (TEG) ,探讨肺癌患者体内凝血状态。方法 对 30例肺癌患者于治疗前进行TEG及常规凝血象的测定 ,另选 10 0例健康人为对照组。结果 绝大多数 (2 9 30 )肺癌患者TEG表现为高凝图象 :γ值 4 4 4± 1 80、K值 2 0 6± 1 73较正常对照组明显缩短 ,Ma值6 6 4 4± 6 4 5、Mε值 2 0 9 79± 6 6 0 7较正常对照组明显增宽 (P <0 0 1)随着病情发展 ,γ、K值缩短及Ma、Mε值增宽更明显。结论 肺癌患者体内存在病理性高凝状态 ,临床可根据TEG的变化诊断肺癌患者凝血状态 ,对判断病情。

Objective To investigate the coagulable states of patients with lung cancer by thrombelastography (TEG) Methods TEG and coagulation routine were measured in 30 patients with lung cancer and 100 normal control.Comparisons were made between lung cancer and normal control Results The hypercoagulable sign of the most lung cancer (29/30) were showed that γ value (4 44±1 80min)、K value (2 06±1 73min) are obvious short and Ma value (66 44±6 45min)、Mε value (209 19±66 07) are obvious wide,compared with normol control ( P <0 01).The hypercoagulable states are more obvious along with the disease progressing.Conclusion The coagulopathy of patients can be diagnosed according to the changes of TEG.It can be used as refereces in judging the condition of patients,to prognose and instract the treatment for patients with lung caucer.