HGV与HBV及HCV在瑶族人群中的感染研究

Study on HGV infection and HBV or HCV infection in Chinese Yao Nationality

目的了解广东瑶族人群庚型肝炎病毒(HGV)感染状况,探讨HGV感染与输血相关肝炎病毒HBV、HCV感染关系。方法采用ELISA法分别检测血清中抗-HGVIgG、HBsAg和抗-HCV。结果1056例血清中检出抗-HGVIgG阳性95例,阳性感染率为9.00%,男性阳性检出率为9.40%,女性阳性检出率为8.63%,男女性别之间差异无统计学意义(χ2=0.189,P>0.05)。抗-HGVIgG阳性检出率随年龄增大而增高,但各年龄组之间差异无统计学意义(χ2=0.437,P>0.05)。抗-HGVIgG+HBsAg、抗-HGVIgG+抗-HCV、抗-HGVIgG+HBsAg+抗-HCV的重叠感染率分别为23.16%、4.55%和4.55%,差异有统计学意义(χ2=21.815,P<0.05)。结论广东瑶族人群存在较高的HGV感染率,HBsAg及抗-HCV均存在HGV重叠感染。

Objective To find out the infection status of HGV in Chinese Yao nationality in Guangdong province, and to explore the relations between HGV infection and HBV or HCV infection. Methods The anti-HGV, HBsAg and anti-HCV were determined by ELISA. Results The positive rate of anti-HGV IgG among the 1 056 individuals was 9.00%; among the male was 9.40% and female was 8.63%. There were no significant differences among the groups of sex and age. The co-infected rates of HGV＋HBV and HGV＋HCV were 23.16% and 4.55%, respectively, showing a significant difference （χ2=21.815, P0.05）. Conclusion The infection rate of HGV was high and showing a higher co-infection of HGV＋HBV than HGV＋HCV among the Yao people in Guangdong province.