非甾体类抗炎药抗肿瘤机理的研究进展

Research Progress in Antitumor Mechanism of Non-Steroidal Anti-Inflammatory Drugs

目的总结非甾体类抗炎药抗肿瘤机理的研究进展。方法查阅近年来国内外关于非甾体类抗炎药抗肿瘤机理的相关文献,就其研究进展进行综述。结果非甾体类抗炎药抗肿瘤的机理是多层次、多位点的。结论非甾体类抗炎药有望成为结直肠癌高危人群的预防用药和结直肠癌根治术后的化疗辅助用药,用于预防术后肿瘤的复发。

Objective To summarize the research progress in antitumor mechanism of non-steroidal anti-inflammatory drugs.Methods The domestic and international published literatures about antitumor mechanism of non-steroidal anti-inflammatory drugs in recent years were reviewed.Results The antitumor mechanism of non-steroidal anti-inflammatory drugs was multistrata and multidigit.Conclusion Non-steroidal anti-inflammatory drugs can be used to prevent the development of colorectal cancer and also be a adjuvant therapy after radical operation for colorectal cancer.