21羟化酶缺乏致女性假两性畸形的内外科联合治疗

Combined treatment of pseudohermaphroditism

目的 为了诊断和治疗 2 1羟化酶缺乏导致的女性假两性畸形。方法 1990年以来 ,对 4例患者进行了外科手术和内科糖皮质激素的综合治疗。结果 4例均得到了一个较完善的女性外阴 ,补充治疗了由于 2 1羟化酶先天缺乏引起的一系列全身症状。结论 综合治疗使该病在临床上获得了满意结果。

Objective\ To diagnose and treat female pseudohermaphroditism caused by 21\|hydroxylase deficiencies.Methods\ Four female patients with 21\|hydroxylase deficiencies have received combined treatment of reconstructive surgery and supplementary glucocorticoid in our hospital since 1990.Results\ The patients obtained a female external genitalias through teh operation.Various symptoms resulted from 21\|hydroxylase deficiency were improved with glucocorticoid therapy.Conclusion\ A satisfying result can be achieved for pseudohermaphroditism by combination of surgery and medicine.\;