我院2011年糖尿病患者尿路感染病原菌分布及耐药性分析

Distribution and Drug Resistance of Pathogenic Bacteria Isolated from Diabetic Patient with Urinary Tract Infection in Our Hospital in 2011

目的:分析糖尿病患者尿路感染病原菌的分布特点及其耐药性。方法:对2011年366例糖尿病患者的临床资料进行回顾性分析,对患者的尿标本进行培养、分离和鉴定,应用纸片扩散(K-B)法进行药敏试验。结果与结论:366例糖尿病患者中,发生尿路感染124例,感染发生率为33.9%,检出菌株102株,检出率为82.3%;其中革兰阴性菌69株(占67.6%),革兰阳性菌21株(占20.6%),假丝酵母菌12株(占11.8%);检出率居首位的为大肠埃希菌,占58.8%(60/102);产超广谱β-内酰胺酶(ESBLs)病原菌总检出率为30.3%(20/66);耐甲氧西林金黄色葡萄球菌(MRSA)检出率为66.7%(6/9)。糖尿病患者尿路感染病原菌耐药形势严峻,应引起临床高度重视。

To analyze the characteristics and drug resistance of pathogenic bacteria isolated from diabetics patients with urinary tract infection. METHODS： Clinical data of 366 diabetes patients in 2011 were analyzed retrospectively. Urine samples of patients were cultured, isolated and identified. And the susceptibility test was performed by K-B method. RESULTS ＆ CONCLUSION： Among the 366 cases of diabetes patients, 124 suffered from urinary tract infections with infection rate of 33.9%. 102 strains were detected with detection rate of 82.3% , among which 69 were Gram-negative bacteria （67.6%） , 21 were Gram-positive bacteria （20.6%） and 12 were Candida （11.8%） ; 60 were Escherichia coli, accounting for the biggest proportion （58.8%）. 20 ESBLs strains were detected （30.3%, 20/66） ; 6 MRSA strains to were produced among 9 Staphylococcus aureus （66.7 %, 6/9）. Drug resistance of pathogenic bacteria to antibiotics is serious, which should he paid attention in clinic.