紫外线治疗特应性皮炎的进展

Advances in the treatment of atopic dermatitis with ultraviolet rays

特应性皮炎是一种慢性复发性炎症性疾病，紫外线通过调节T细胞功能及相关炎症介质而取得良好疗效。不同波段紫外线因其特性而应用于不同类型的特应性皮炎：窄谱中波紫外线治疗儿童期特应性皮炎显示出良好疗效及安全性，认为是慢性患者的首选治疗；急性患者首选长波紫外线照射；局限性皮损选择308nm准分子激光为佳。紫外线治疗特应性皮炎临床尚处于初级阶段，在照射剂量和照射疗程方面，各家报道不一。

Atopic dermatitis is a chronic recurrent inflammatory disease. By regulating the function of T cells and related inflammation factors, ultraviolet rays （UV） exert a satisfactory therapeutic effect on atopic dermatitis. Because of distinct characteristics, different spectrum of UV is applicable to specific types of atopic dermatitis. Narrow-band UVB shows good efficacy and safety in the treatment of atopic dermatitis in childhood, and is considered to be the best choice for patients with chronic atopic dermatitis; UVA is the preferred choice for patients with acute atopic dermatitis, and 308-nm excimer laser is suitable for local lesions of atopic der- matitis. However, there has been no uniform standard for the dose and duration of UV irradiation in the treat- ment of atopic dermatitis.