苯扎溴铵/二氧化硅杂化抗菌材料的制备和性能研究

Preparation of benzalkonium bromide/silica composite antibacterial material and investigation on performance thereof

研究了以碱性硅溶胶、十二烷基二甲基苄基溴化铵为原料,通过共沉淀制备杂化抗菌材料的方法。采用低温氮吸附、SEM和FT-IR手段表征了样品的比表面、颗粒形貌和表面基团;通过抑菌圈实验表征了样品对于金色葡萄球菌的抑制能力,并通过摇床实验表征了材料的耐溶出性能。研究发现本方法所制备的有机-无机杂化材料抗菌性能较好,并具有一定的耐溶出性能,有望作为缓释抗菌材料而应用于涂料或高分子材料中。

Composite antibacterial mate rials were prepared via co-precipitation method with basic silica sol and dodecyl dimethyl benzyl ammonium chloride as raw materials.Low-temperature N2 adsorption,SEM,and FT-IR methods were employed to characterize the BET specific surface area, particle morphology, and surface functional groups of the as-made samples. Bactcriostasis circle experiments were conducted to assess the dissolving antibacterial performance of the samples upon staphylococcus aureus.Sustained-release ability of the as-made samples was investigated with dissolving experiment on rotary shaker.It was revealed by the results that as-made organic/inorganic composite antibacterial material show obvious antibacterial performance and good sustained-release ability.The composite materials are expected to be applied in paint or polymer as controlled-releasing antibacterial element.