桃红四物汤化裁对恶性肿瘤并发弥散性血管内凝血疗效观察

Clinical Observation of Treating Malignant Tumor with DIC with Modified Taohong Siwu Decoction

目的:观察中药桃红四物汤化裁治疗肿瘤弥散性血管内凝血的临床疗效。方法:将96例患者随机分为治疗组54例和对照组42例;两组均在积极治疗原发病的基础上,对照组给予抗凝抗纤溶治疗,治疗组同时辨证给予中药桃红四物汤加减化裁。两组均治疗14 d,观察临床疗效及症状变化情况,并检测PLT、Fbg、APTT、PT、FDP、D-二聚体。结果:治疗组临床症状变化及其改善时间较对照组快(P<0.05);治疗组PLT、Fbg、APTT、PT、FDP、D-二聚体等实验室较对照组明显改善(P<0.05);治疗组治疗结果优于对照组(P<0.05)。结论:中药桃红四物汤化裁治疗较单纯西医治疗能够明显提高恶性肿瘤弥散性血管内凝血的临床疗效。

Objective ： To study clinical effect of modified Taohong Siwu Decoction on treating malignant tumor with DIC. Meth- ods ：96 patients were randomly divided into treatment group（ n = 54） and control group（ n = 42）. All the patients were given con- ventional treatment, and the patients in the treatment group received modified Taohong Siwu Decoction in addition. The changes of main symptoms were evaluated and the index of coagulation was monitored. Results：The main symptoms such as bleeding in the skin, time of symptom improvement in the treatment group were lower than those in control treatment （ P 〈 0. 05 ）. The index of prognosis was better in the treatment group than that in control group （ P 〈0. 05）. Conclusion ： Modified Taohong Siwu Decoction may effectively treat malignant tumor with DIC.