推拿治疗缓解疼痛的机理探讨

Exploration for Mechanisms of Pain—Relieve by Massotherapy

我们测定了100例中老年腰椎间盘突出症患者推拿牵引治疗前后尿中巯基(-SH)及钾含量的变化。患者在治疗前,尿中-SH均值为776.20±33.76mmol/L,中位数(M)=515.04mmol/L;经首次治疗后,降为217.42±9.74mmol/L,M=180.92mmol/L,平均下降62%。治疗前后尿-SH含量的差别有极显著意义(P<0.01)。治疗前尿钾均值为29.92±3.0mmol/L,M=17.65mmol/L;首次治疗后降为11.49±0.96mmol/L,M=7.58mmol/L,平均下降58%。治疗前后尿钾含量的差别有极显著意义(P<0.01)。尿中两种物质下降的幅度和疗效(疼痛缓解)之间呈现明显的平行关系,疗效越理想,-SH和K^+含量的下降越明显。病情有反复时,尿中两种物质的含量也相应回升。关于-SH和疼痛之间这种关系的发现。将为疼痛的研究提供一个崭新的内容。本文对此种关系的可能机制进行了初步推测。

The relationship between sulfhydryl groups and pain was first discovered by the authors. One hundred cases of urinary sulfhydryl groups and potassium levels of the patients suffering from lumbar intervertebral disc protrusion were meassured pre-and post-treatment with massage and traction. Before treatment, the average level of urinary-SH was 776.20±33.76mmol ((?)+SE), but the level was lowered to 717.42±9.74mmol/L after first treatment (P<0.01), the lower range was ranging from 33%～91%(62% on the average). Potassium was 116.88±1.17mg% before treatment, and was down to 44.90±3.76mg% after first treatment(P<0.01). The decrease extent was 20～96% (58% on the average). A great parallel exists between falling extent of these 2 substances in urine and curative effect(pain relief). The more satisfactory in cure, the more decrease in the content of -SH and K^+. These 2 substances (-SH, espacially) would be raising again when pain is getting severe. The mechanisms were postulated.