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帕瑞昔布钠对雷米芬太尼致老年骨科术后痛觉过敏的预防效果 被引量:2

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摘要 雷米芬太尼多作为一种阿片受体激动剂,在临床用于静脉麻醉,其特点为起效快、镇痛效果好及可控性好等;但雷米芬太尼镇痛作用时间较短,消退的速度较快,这样就直接造成患者痛觉过敏。而帕瑞昔布钠是一种环氧化酶抑制剂,直接通过选择性抑制环氧化酶活性,从而减少前列腺素合成,降低患者术后痛觉过敏的发生几率。本文通过观察帕瑞昔布钠对雷米芬太尼致老年骨科术后痛觉过敏的预防效果,探讨帕瑞昔布钠来弥补雷米芬太尼在老年骨科手术镇痛的不足。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第1期206-207,共2页 Chinese Journal of Gerontology
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