期刊文献+

如何切实有效地开展胃肠肿瘤的转化医学研究 被引量:7

How to carry out the translational medicine research effectively in gastrointestinal tumors
原文传递
导出
摘要 转化医学作为医学发展的新理念,虽然定义尚未明确,但其作为连接临床医学和实验室之间的桥梁,重要性已日益凸显。胃肠外科的发展始终体现着转化医学的理念。为开展转化医学研究,胃肠外科医师必须学习从临床中寻找研究问题,完整收集临床资料,重视团队协作,特别是跨学科的合作,同时充分利用各种资源。通过转化医学研究,胃肠外科医师能够进一步提高我国胃肠道肿瘤的综合诊治水平,提高患者长期生存率。 As new concept, the definition of translational medicine remains obscure. The translational medicine connects the bench to bedside, and its importance wouht be more remarkable. The development of gastrointestinal surgel'y reflects the idea of translational medicine. To carry out the translational study, the gastrointestinal surgeon must learn how to find subjects from clinical problems, how to collect complete information and tissues, bow to collaborate with others from different fields and how to utilize all kinds of resources. By translational studies, gastrointestinal surgeons may further improve the survival of patients with gastrointestinal tumor.
出处 《中华胃肠外科杂志》 CAS CSCD 2013年第1期1-3,共3页 Chinese Journal of Gastrointestinal Surgery
关键词 胃肠肿瘤 转化研究 转化医学 Gastrointestinal neoplasms Translationalstudy Translational medicine
  • 相关文献

参考文献8

  • 1Choi DW. Bench to bedside:the glutamate connection[J].Science,1992.241-243.
  • 2Geller RB,Karp JE. Adult acute leukemia:a need for continued translational research[J].Blood,1994.3980-3981.
  • 3Geraghty J. Adenomatous polyosis coli and translational medicine[J].The Lancet,1996.422.
  • 4Zerhouni E. Medicine,the NIH Roadmap[J].Science,2003,(5642):63-72.
  • 5Contopoulos-Ioannidis DG,Ntzani E,Ioannidis JP. Translation of highly promising basic science research into clinical applications[J].American Journal of Medicine,2003.477-484.
  • 6Ioannidis JP. Materializing research promises:opportunities,priorities and conflicts in translational medicine[J].Journal of Traditional Medicines,2004.5.
  • 7Maleddu A,Pantaleo MA,Nannini M. The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting[J].Journal of Traditional Medicines,2011.75.
  • 8田玲,张宏梁,马凌飞.国内外转化医学发展现状与展望[J].医学研究杂志,2011,40(1):17-20. 被引量:45

二级参考文献39

  • 1Lehmann CU,Altuwaijri MM,Li YC,et al.Translational research in medical informatics or from theory to practice.Methods of information in medicine,2008,47(1):1-3.
  • 2Littman BH,Mario LD,Plebani M,et al.What′s next in translational medicine.Clinical Science,2007,112(4):217-227.
  • 3Marincola FM.Translational Medicine:A two way road.Journal of Translational Medicine,2003,1(1):1-2.
  • 4Choi DW.Bench to bedside:the glutamate connection.Science,1992,258(5080):241-243.
  • 5Geraghty J.Adenomatous polyposis coli and translational medicine.Lancet,1996,348(9025):422.
  • 6Editorial.Human capital in translational research.Nature Reviews Drug Discovery,2008,7(6):461.
  • 7Wadman M.Harvard turns to matchmaking to speed translational research.Nature Medicine,2008,14(7):697.
  • 8DiGiusto DL,Krishnan A,Li L,et al.RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma.Science Translational Medicine,2010,2(36):36-43.
  • 9Wu CL,Jordan KW,Ratai EM,et al.Metabolomic Imaging for Human Prostate Cancer Detection.Science Translational Medicine,2010,2(16):16-18.
  • 10Stott SL,Lee RJ,Nagrath S,et al.Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer.Science Translational Medicine 2010,2(25):23-25.

共引文献44

同被引文献96

引证文献7

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部