刺络放血与西药治疗皮肤瘙痒症疗效对照观察

Controlled observation on efficacy between blood-letting puncture and western medication for cutaneous pruritus

目的:比较刺络放血与西药治疗皮肤瘙痒症的临床疗效差异,为皮肤瘙痒症提供更为有效的治疗方法。方法:60例皮肤瘙痒症患者随机分为刺络组与西药组,每组30例。刺络组采用梅花针叩刺皮损处,叩至局部皮肤潮红,并见隐隐出血为度;西药组口服抗组胺药氯苯那敏片,比较两组患者治疗前后瘙痒积分,并评定两组临床疗效。结果:刺络组总有效率为93.3%(28/30),优于西药组的73.3%(22/30,P<0.05);两组治疗后瘙痒积分均较治疗前降低(刺络组7.33±0.96vs1.75±0.68,西药组7.38±0.97vs 3.25±2.07,均P<0.05),治疗后刺络组瘙痒积分低于西药组(P<0.05);刺络组无明显不良反应,西药组分别出现嗜睡24例、头痛4例、口干5例。结论:刺络放血治疗皮肤瘙痒症疗效确切,优于西药氯苯那敏片,且无明显不良反应。

Objective To compare clinical efficacy difference between blood-letting puncture and western medicine, and provide a more effective treatment method for cutaneous pruritus. Methods Sixty cases of cutaneous pruritus were randomly divided into a blood-letting puncture group and a western medication group cases in each one. The plum-blossom needle was applied at damaged skin area till slight flushing on the local skin in the blood-letting puncture group, while chlorphenamine was prescribed orally for the western medication group. The pruritus score and clinical efficacy of two groups before and after treatment were observed and compared. Results The total effective rate was 93.3% （28/30） in the blood-letting puncture group, which was superior to 73.3%（22/30） in the western medication group（P〈0. 05）. Compared before treatment, the pruritus score of two groups were decreased after treatment respectively, which was （7.330.96 vs 1.75±0.68） in the blood letting puncture group and （7.38±0.97 vs 3.25±2.07） in the western medication group （both P〈0.05）. After treatment, the pruritus score in the blood letting puncture group was lowered than that in the western medicine group （P〈0. 05）. There was no adverse reaction in the blood-letting puncture group, while there were 24 cases with somnolence, 4 cases with headache and 5 cases with dry mouth in the western medication group. Conclusion The blood-letting puncture has positive efficacy for cutaneous pruritt, s without obvious adverse reaction and it is better than western medicine therapy.