肾上腺髓质增生症(附八例报告)

Adrenal medullary hyperplasia (report of 8 cases)

目的 提高肾上腺髓质增生症 (AMH)的诊断水平和治疗效果。 方法 回顾总结1993年 12月～ 1999年 6月收治 8例AMH患者的临床资料。 结果 经影像学检查 ,8例中 5例肾上腺和肾上腺外未发现肿瘤 ,诊断为AMH ;3例因肾上腺占位性病变诊断为嗜铬细胞瘤。 7例行单侧肾上腺切除术 ,5例痊愈 ,2例病情改善 ;1例行双侧肾上腺全切除、带血管去髓质自体肾上腺移植术 ,术后痊愈。 结论 AMH临床诊断应首先排除嗜铬细胞瘤 ,确诊需经病理检查 ,手术为治疗AMH的主要方法。

Objective To study the diagnosis and treatment of adrenal medullary hyperplasia. Methods From Dec.1993 to June.1999,8 cases of analysed adrenal medullary hyperplasia have been trea ted and followed up.The diagnosis,treatment and late follow up results were studied and reviewed. Results All the cases were verified on catecholamin aassay (CA).In 5 of the patients,there was no tumor mass found on imaging procedures either in the adrenal gland or outside the gland.An adrenal tumor mass was noted in 3 cases and a diagnosis of pheochromocytoma has been made.7 patients underwent unilateral adrenalectomy with 5 cured of the disease and 2 improved.Bilateral adrenalectomy and pedicled autotransplantation of medullary excised adrenal gland was undertaken for the other patient with satisfactory outcome. Conclusions Pheochromocytoma should be first excluded on imaging examination and the diagnosis of adrenal medullary hyperplasia should be verified by CA assay.The final diagnosis depends on patholo gical studies.The treatment of choice is surgical.