摘要
白毛藤多糖以不同浓度作用于胰腺癌细胞,采用Hoechst33258染色测定凋亡情况,RT-PCR检测caspase-3蛋白的表达。结果表明,白毛藤多糖的抗肿瘤作用可能与细胞凋亡有关。
Pancreas carcinoma cells were treated with various concertratoion of Solamum lyratum polysaccharides, Hoechst33258 dyeing was used to detect the apoptosis of pancreas carcinoma cells in various concentration of Solamum lyratum polysaccharides, and RT-PCR was used to detect the expression ofcaspase -3. Results showed that Solamum lyratum polysaccharides could inhibit the pancreas carcinoma prolif- eration by regulating apoptosis.
出处
《中国食物与营养》
2012年第12期64-65,共2页
Food and Nutrition in China
基金
黑龙江省中医药管理局中医药科研项目"白毛藤诱导肿瘤细胞凋亡有效成分筛选及其机制研究"(项目编号:ZHY10-W71)
关键词
白毛藤多糖
胰腺癌细胞
细胞凋亡
Solamum lyratum polysaccharides
pancreas carcinoma cells
cell apoptosis
