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A simple and efficient procedure for the synthesis of optically active s-triazolothiadiazole derivatives

A simple and efficient procedure for the synthesis of optically active s-triazolothiadiazole derivatives
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摘要 A series of novel s-triazolothiadiazoles 3a-h were prepared by condensation reaction of substituted amino triazoles 1a-b with N-phethaloyl-L-amino acids 2a-d in the presence of the phosphoroxy chloride (POC13) as an anhydrous reagent. The structure of all synthesized compounds was confirmed by IR, 1H NMR, arid 13C NMR spectroscopy. A series of novel s-triazolothiadiazoles 3a-h were prepared by condensation reaction of substituted amino triazoles 1a-b with N-phethaloyl-L-amino acids 2a-d in the presence of the phosphoroxy chloride (POC13) as an anhydrous reagent. The structure of all synthesized compounds was confirmed by IR, 1H NMR, arid 13C NMR spectroscopy.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第12期1335-1338,共4页 中国化学快报(英文版)
基金 Malayer Branch,Islamic Azad University for their financial support
关键词 s-Tfiazolothiadiazole L-Amino acid 1 2 4-Triazole-3-thiol Optical activity Phosphorus oxychloride s-Tfiazolothiadiazole L-Amino acid 1,2,4-Triazole-3-thiol Optical activity Phosphorus oxychloride
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