MASPIN在肿瘤血管生成中的作用
The role of maspin in tumor angiogenesis
摘要
MASPIN基因是丝氨酸蛋白酶抑制剂超家族中的新成员。大量研究发现它作为肿瘤抑制基因对肿瘤的生长、侵袭、转移有明显抑制作用,近来更被证实是一种有效的血管生成抑制因子。本综述总结了MASPIN在肿瘤血管生成中所发挥的作用,探讨及其可能的分子机制,旨在为以MASPIN为分子靶点的抗肿瘤基因治疗提供理论依据。
出处
《实用医院临床杂志》
2013年第1期165-168,共4页
Practical Journal of Clinical Medicine
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