地奈德乳膏联合尿素乳膏治疗手部湿疹疗效及生活质量分析

Curative effect and life quality analysis of desonide cream combined with urea cream in the treatment of hand eczema

目的研究分析地奈德乳膏联合尿素乳膏对于患者手部湿疹的治疗效果,并探讨患者生活质量。方法选择我院在2010年10月～2011年10月收治的手部湿疹患者100例。将所有患者随机分为两组,观察组和对照组各50例。对照组采用丁酸氢化可的松乳膏联合10%尿素乳膏治疗,观察组采用地奈德乳膏联合10%尿素乳膏治疗。两组患者用药均为2次/d,并且连续用药2周。对两组治疗2周后的临床效果做比较,并对两组患者的生活质量做相应的问卷调查。结果观察组治疗有效率为92%,明显高于对照组64%的治疗有效率,差异具有统计学意义,P<0.05。观察组患者在生活质量改善程度上也明显优于对照组,差异具有统计学意义,P<0.05。结论采用地奈德乳膏联合尿素乳膏治疗手部湿疹的治疗效果比较好,并且能够有效改善患者的生活质量,值得在临床上广泛运用。

Objective To study the analysis of desonide cream combined with urea ointment for patients with hand eczema treatment, and to explore the quality of life of patients. Methods Collected 100 patients with hand eczema in our hospital during October 2010 to October 2011 and randomly divided into two groups, the observe group and refer- ence group, each group had 50 cases. Patients in the reference group were treated with hydrocortisone butyrate cream combined with 10% urea cream while patients in the observe group using desonide cream combined with 10% urea cream. Both groups of patients were 2/d, and took medicate for 2 weeks. After two weeks, compared the clinical ther- apeutic effects, and did some corresponding questionnaire survey on their quality of life. Results About 92.16% of pa- tients were cured in the observe group, much better than the reference group which 64% efficiency, the difference be- tween two groups was statistically significant, P 〈 0.05. The observe group got an improvement in their quality of life, also significantly better than the reference group. Results between two groups was statistically significant, P〈0.05. Conclusion For the treatment of hand eczema patients, using desonide cream combined with urea cream therapeutic worthy widely used in clinical application, which can get better result and effectively improve their quality of life.