25例产科弥散性血管内凝血的临床探讨

Influencing factors of disseminated intravascular coagulation in obstetric:An analysis of 25 cases

目的探讨25例产科弥散性血管内凝血患者的诱发因素和治疗效果。方法回顾性分析25例产科弥散性血管内凝血患者凝血及纤溶系统水平及诱发因素。结果产科弥散性血管内凝血的发生率为0.119%,其诱发性因素主要包括产后出血、妊高征、胎盘早剥、羊水栓塞和死胎等。结论产科弥散性血管内凝血患者会出现明显的凝血及纤溶功能异常,早期预防、早期诊断、早期治疗是基本原则。

Objective To analysis of influencing factors in 25 patients of obstetric disseminated intravascular coagula- tion （DIC）. Methods Retrospective analysis of coagulation and fibrinolysis system level and predisposing factors in 25 cases of obstetric patients with DIC. Results The incidence rate of obstetric DIC in all the maternity patients was 0.119%. The main factors leading to DIC consist of postpartum hemorrhage, pregnancy-induced hypertension, placen- tal abruption, amniotic fluid embolism, and stillbirth. Conclusion Obstetric DIC occurs in patients with significant dysfunction of coagulation and fibrinolysis. To make earlier diagnosis, and treatment play a vital role in treating those patients with DIC.