自拟调脉汤联合西药治疗老年病态窦房结综合征疗效观察

Obsevation on clinical effect of self-made Tiaomai decoction combined with western medicine in treating senile sick sinus syndrome

目的观察自拟调脉汤联用西药治疗老年病态窦房结综合征的临床疗效。方法将100例老年病态窦房结综合征患者随机分为对照组50例和治疗组50例,对照组在原发病治疗基础上口服山莨菪碱10 mg、沙丁胺醇2.4mg,每日3次;治疗组在对照组基础上加服自拟调脉汤,每日1剂,1疗程为15日,2个疗程后判定疗效。结果总有效率治疗组为88.0%,对照组为60.0%。治疗组总有效率明显高于对照组(P<0.01)。两组患者治疗后心率、心电图指标均有改善,但治疗组改善疗效均明显优于对照组(P<0.01)。结论自拟调脉汤联用西药治疗老年病态窦房结综合征疗效显著,安全性好。

Objective To observe the clinical effects of self - made Tiaomai decoction combined with western medicine in treatment of senile sick sinus syndrome （SSS） . Methods One hundred patients with SSS were randomly divided into western medicine （WM） control group （ n = 50） and traditional and western medicine （TWM） treatment group （n = 50）. Patients in control group accepted oral administration of anisodamine 10 mg and salbutamol 2.4 mg, 3 times daily. Patients in TWM treatment group were additionally given with Tiaomai Tang （decoction）, one dose per day, and the therapeutic course of both groups was 15 days. The curative effects were observed after 2 courses of treatment. Results After treatment, the total effective rate of TWM treatment group was 88% , it was obviously higher than that （60%） of control group （ P 〈0. 01 ） . Heart rate and ECG had been improved in patients of these two groups, but their difference was remarkable （ P 〈0.01 ）. Conclusion The application of self - made Tiaomiao decoction combined with western medicine in treatment of senile sick sinus syndrome has remarkable effects and good safety.