解脲支原体感染与不良妊娠结局的相关性

Study on relationship between Ureaplasma urealyticum infection and adverse pregnancy outcomes

目的探讨女性解脲支原体(UU)感染与不良妊娠结局的相关性。方法用荧光定量聚合酶链反应法对流产患者和正常妊娠孕妇宫颈分泌物进行UU检测,对母亲有UU感染的住院新生儿痰进行UU检测。结果 508例流产患者UU感染率为47.24%,214例正常妊娠孕妇UU感染率为24.77%;两组感染率差异有统计学意义(P<0.05)。UU母婴传播率为32.04%,UU感染患儿主要临床表现为早产、肺炎、肺透明膜症。结论南宁地区妇女UU感染与流产密切相关,孕期UU感染可导致多种新生儿疾病的发生。

Objective To explore the relationship between Ureaplasma urealyticum （Uu） infection and adverse pregnancy outcomes. Methods Ureaplsma urealyticum can be detected by using fluorescence quantitative polymerase chain reaction in cervical secretions of women with spontaneous abortion and normal pregnancy, and sputa of neonatal infants were examined for Uu. Results Among 508 cases of abortion, the infection rate of Uu was 47.24%, and that was 24.77% in 214 women with normal pregnancy. There was statistically significant difference in infection rate of Uu between women with abortion and normal fetation controls （ P 〈 0.05 ）. The rate of mother - to - child transmission was 32. 04%, and premature birth, pneumonia and lung transparent film disease were the main clinical manifestations of patients infected with Uu. Condusion Infection of Uu in pregnant women is closely related with spontaneous abortion in Nanning, and Uu infection may lead to a variety of neonatal diseases.